Monday, July 31, 2006

Depression? Headache? Danger!

Well our friends at the Food and Drug Administration have posted an advisory warning about the mixing of certain antidepressants in the SSRI/SNRI category along with triptans. It turns out that since both have the effect of elevating serotonin, there's a risk of something called "serotonin syndrome."

A few points regarding this advisory:

  • Apparently, this syndrome is pretty serious, but the number of cases is, so far, relatively small.
  • Not all doctors are aware of this, and the drug manufacturers websites don't seem to have been updated yet with details of the advisory (as of earlier this week).
  • Effexor (Venlafaxine) is one of the SNRI drugs that is specifically called out in the advisory, and it so happens that it is also one of the tricyclic antidepressants that is sometimes prescribed as a migraine preventative (hmmm).
If I were taking an SSRI/SNRI and a triptan at the same time, I might really consider scheduling a consult with my headache doc ASAP to see if they wanted me to switch drugs.

Here's a link to the FDA advisory:


At Friday, August 01, 2008 10:07:00 PM, Blogger n1x5icbk said...

as I know from a book titled " Avoid Addiction to medicine " that migraine can also be caused by the decrease of levels of elasticity, density, muscle structure, sensitivity nerve and disturbed blood stream.
Pennasia Normalization is the way of healing for normalizing the process of reaction
happening in body optimally. For further, you can learn this healing way and visit us at

At Sunday, November 30, 2008 6:49:00 PM, Anonymous Anonymous said...

Hello i am a french and i have a book about the migraines/headache strong:

At Wednesday, March 18, 2009 6:22:00 AM, Blogger super said...

People who think that they are suffering from depression should consult a psychologist. It is the psychologist's job to determine what kind of therapy is needed by the person suffering from depression. After being diagnosed by the psychologist, the services of a psychiatrist could also be needed. It is the psychiatrist who gives the prescription on the drugs that will help in balancing the chemical imbalances in the brain. Depressed people can easily be treated with the help of medicines and series of therapy sessions in order to help the person determine cause of their depression.

At Tuesday, June 23, 2009 2:11:00 PM, Blogger seller said...

very good post


Post a Comment

Links to this post:

Create a Link

<< Home

Contents Copyright ©2006 Robert M. Streno
This blog is intended as a journal of my own personal experiences with migraine, and should not be used for any type of self-diagnosis. If you believe that you have a medical condition that needs addressed, please see a doctor.